Joshua Lederberg 1925–2008

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Joshua Lederberg 1925–2008

It is painful to start writing an article destined to be an Obituary for a dear friend and a great scientist. To describe Joshua Lederberg as a " polymath " would be an enormous understatement. He made seminal contributions to the fields of microbiology and molecular biology and also to artificial intelligence, organic chemistry, exobiology, and many other disciplines. Joshua Lederberg was born...

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Joshua Lederberg (1925-2008)

Lederberg’s many and varied contributions, particularly to the diverse sciences he mastered and bridged, have been well documented, so the focus here is on his contributions to computing. His interest in computing, he told me, started with his experience programming a card reader to do computations in high school. Although his lifelong fascination with programming machines to help us think was ...

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Joshua Lederberg on Bacterial Recombination.

This paper describes the first genetic analysis of bacteria. Before its publication,most scientistswondered if bacteria even had genes. Many thought bacteria to be a distinct form of life, separate from higher organisms like Drosophila and maize, which were known to follow Mendel’s principles of heredity. But when George Beadle and Edward Tatum showed in 1941 that Neurospora obeys Mendel’s laws...

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In Memoriam: Joshua Lederberg (1925–2008)1

he world of emerging infections lost a valuable friend and inspiring leader earlier this year with the death of Joshua Le-derberg. The globally recognized scientist, educator, national and Presidential scientifi c advisor, and Nobel Laureate died of pneumonia on February 2, 2008, at the age of 82. Dr Lederberg's early work on bacterial genetics virtually established the discipline of molecular ...

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Science as oath and testimony: Joshua Lederberg (1925-2008).

Josh Lederberg was already worried a generation ago: “One of the major trends of scientific writings for the past century is the systematic falsification of the actual techniques and method of discovery (1).” Lederberg wasn’t concerned that published papers fail to mention the false starts, wrong turns, or dead ends on the road to discovery. He accepted the conventional forms of scientific publ...

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ژورنال

عنوان ژورنال: Cell

سال: 2008

ISSN: 0092-8674

DOI: 10.1016/j.cell.2008.02.021